Sadanandan E Velu Selected Research

iminoquinone

7/2015	Development and validation of an HPLC-MS/MS analytical method for quantitative analysis of TCBA-TPQ, a novel anticancer makaluvamine analog, and application in a pharmacokinetic study in rats.
7/2013	Identification of the ZAK-MKK4-JNK-TGFβ signaling pathway as a molecular target for novel synthetic iminoquinone anticancer compound BA-TPQ.
9/2010	A novel synthetic iminoquinone, BA-TPQ, as an anti-breast cancer agent: in vitro and in vivo activity and mechanisms of action.
7/2010	Preclinical pharmacology of BA-TPQ, a novel synthetic iminoquinone anticancer agent.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Sadanandan E Velu Research Topics

Disease

16	Neoplasms (Cancer) 04/2021 - 05/2009
7	Breast Neoplasms (Breast Cancer) 01/2018 - 05/2009
4	Neoplasm Metastasis (Metastasis) 04/2021 - 12/2016
3	Dental Caries (Decay, Dental) 07/2018 - 08/2015
2	Hepatocellular Carcinoma (Hepatoma) 10/2019 - 01/2017
2	Pancreatic Neoplasms (Pancreatic Cancer) 10/2018 - 05/2012
2	Lung Neoplasms (Lung Cancer) 09/2013 - 05/2009
1	Sarcoma (Soft Tissue Sarcoma) 04/2021
1	Dementia (Dementias) 01/2021
1	Nervous System Diseases (Neurological Disorders) 01/2021
1	Alzheimer Disease (Alzheimer's Disease) 01/2021
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 10/2020
1	Skin Neoplasms (Skin Cancer) 07/2019
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 07/2019
1	Renal Cell Carcinoma (Grawitz Tumor) 12/2018
1	Pain (Aches) 01/2018
1	Liver Neoplasms (Liver Cancer) 01/2017
1	Adenocarcinoma 01/2016
1	Squamous Cell Carcinoma of Head and Neck 08/2015
1	Body Weight (Weight, Body) 08/2015
1	Glioblastoma (Glioblastoma Multiforme) 09/2013
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2013
1	Asthma (Bronchial Asthma) 06/2011
1	Respiratory Hypersensitivity 06/2011
1	Ovarian Neoplasms (Ovarian Cancer) 01/2011
1	Prostatic Neoplasms (Prostate Cancer) 06/2010
1	Influenza in Birds (Avian Flu) 07/2003
1	Human Influenza (Influenza) 07/2003

Drug/Important Bio-Agent (IBA)

5	Pharmaceutical PreparationsIBA 01/2021 - 08/2015
4	Antineoplastic Agents (Antineoplastics)IBA 07/2019 - 05/2009
4	7- (benzylamino)- 1,3,4,8- tetrahydropyrrolo(4,3,2- de)quinolin- 8(1H)- oneIBA 01/2017 - 07/2010
4	Proteins (Proteins, Gene)FDA Link 01/2017 - 05/2009
4	iminoquinoneIBA 07/2015 - 07/2010
4	7- (4- fluorobenzylamino)- 1,3,4,8- tetrahydropyrrolo(4,3,2- de)quinolin- 8(1H)- oneIBA 05/2012 - 05/2009
3	MA242IBA 04/2021 - 10/2018
3	Oncogene Proteins (Oncogene Protein)IBA 04/2021 - 10/2018
3	Biological ProductsIBA 07/2019 - 05/2009
2	Voltage-Gated Sodium ChannelsIBA 04/2021 - 01/2018
2	Biomarkers (Surrogate Marker)IBA 04/2021 - 12/2016
2	Phosphotransferases (Kinase)IBA 01/2021 - 09/2013
2	EnzymesIBA 01/2016 - 01/2016
2	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2016 - 01/2015
2	AlkaloidsIBA 01/2011 - 05/2009
1	SodiumIBA 04/2021
1	tyrosine receptor (receptor, tyrosine)IBA 01/2021
1	Therapeutic UsesIBA 01/2021
1	Plant ExtractsIBA 01/2021
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2021
1	PyrroloiminoquinonesIBA 07/2019
1	Oxidoreductases (Dehydrogenase)IBA 12/2018
1	Gemcitabine FDA Link 10/2018
1	Sodium Channel BlockersIBA 01/2018
1	Protein Isoforms (Isoforms)IBA 01/2018
1	Anti-Arrhythmia AgentsIBA 01/2018
1	HydrogelsIBA 01/2017
1	Toll-Like Receptor 9IBA 12/2016
1	Diphosphonates (Bisphosphonates)IBA 12/2016
1	Small Interfering RNA (siRNA)IBA 12/2016
1	PoisonsIBA 01/2016
1	Type I DNA Topoisomerases (Topoisomerase I)IBA 01/2016
1	Sucrose (Saccharose)IBA 01/2016
1	Adenosine Triphosphate (ATP)IBA 01/2016
1	Sulfhydryl Compounds (Thiols)IBA 01/2016
1	Aconitate Hydratase (Aconitase)IBA 01/2016
1	GlucansIBA 01/2016
1	triphenylphosphoniumIBA 01/2016
1	ErbB Receptors (EGF Receptor)IBA 08/2015
1	honokiolIBA 08/2015
1	Gefitinib (Iressa)FDA Link 08/2015
1	CyclinsIBA 08/2015
1	Cell Cycle ProteinsIBA 08/2015
1	Sirolimus (Rapamycin)FDA Link 08/2015
1	PhytochemicalsIBA 08/2015
1	Nonsense Codon (Nonsense Mutation)IBA 01/2013
1	ArginaseIBA 06/2011
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 06/2011
1	Superoxides (Superoxide)IBA 06/2011
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 06/2011
1	FITC-annexin A5IBA 01/2011
1	PromegaIBA 01/2011
1	AnnexinsIBA 09/2010
1	Hormones (Hormone)IBA 09/2010
1	CaspasesIBA 05/2009
1	AminesIBA 07/2003
1	Benzoic Acid (Potassium Benzoate)FDA Link 07/2003
1	Guanidine (Guanidine Nitrate)FDA Link 07/2003
1	Neuraminidase (Sialidase)IBA 07/2003

Therapy/Procedure

9	Therapeutics 10/2018 - 05/2009
2	Investigational Therapies (Experimental Therapy) 01/2011 - 06/2010